Conference Proceedings

Evaluating the PET Parameters SUVmax and TMTV in the Setting of Autologous Stem Cell Transplantation for DLBCL

Rachel Brown, Alessandro Lambertini, Michael S Hofman, Mathias Bressel, Michael P Macmanus, Andrew Wirth, John F Seymour, Michael Dickinson, Belinda Campbell

BLOOD | AMER SOC HEMATOLOGY | Published : 2020

Abstract

Introduction Where tolerated,high dose chemotherapy supported by autologous stem cell transplantation (ASCT) is the standard of care for patients with relapsed or refractory diffuse large B cell lymphoma (DLBCL). Disease recurrence post-ASCT however is common and carries an extremely poor prognosis, highlighting the need for improved pre-transplant prognostic stratification. This study investigates the prognostic utility of the PET parameters total metabolic tumour volume (TMTV) and standardised uptake value (SUV)max in the peri-transplant setting. Methods 125 patients underwent ASCT for relapsed or refractory DLBCL between 1/1/2002 and 31/1/2017 ..

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