When Eating Becomes a Pain in the Gut
Taylor Adair, Gabrielle T Belz
TRENDS IN IMMUNOLOGY | ELSEVIER SCI LTD | Published : 2021
Irritable bowel syndrome often appears following gastrointestinal infection and is marked by diarrhea, dysbiosis, fever, and intestinal pain following eating. A recent study by Aguilera-Lizarraga et al. now demonstrates that a breakdown in intestinal immunotolerance sparks an inflammatory response to typically tolerated food antigens and causes visceral pain.
This work was funded by the National Health and Medical Research Foundation (Australia) and a University of Queensland Grant (G.T.B.) .