Bacterial biofilm formation on vaginal ring pessaries used for pelvic organ prolapse
Felicity G Gould, Marcus P Carey, Erica L Plummer, Gerald L Murray, Jennifer A Danielewski, Sepehr N Tabrizi, Suzanne M Garland
INTERNATIONAL UROGYNECOLOGY JOURNAL | SPRINGER LONDON LTD | Published : 2021
INTRODUCTION AND HYPOTHESIS: The objective of this study was to characterize the bacterial biofilm on vaginal ring pessaries used to treat pelvic organ prolapse and investigate the relationship between biofilm phenotype and patient symptoms and clinical signs that are suggestive of inflammation. METHODS: This was a cross-sectional observational study of 40 women wearing a ring-shaped pessary continuously for at least 12 weeks. Participants underwent a clinical examination, and the pessary was removed. Clinical signs were recorded. A swab from the pessary surface and a high vaginal swab were collected from each woman. Participants completed a questionnaire on symptoms. Pessary biofilm presenc..View full abstract
This work was supported by a grant from the Urogynaecology Special Purpose Fund, The Royal Women's Hospital, Melbourne, Australia.