Journal article

Dipylidium caninum draft genome - a new resource for comparative genomic and genetic explorations of flatworms.

Guo-Hua Liu, Pasi K Korhonen, Neil D Young, Jiang Lu, Tao Wang, Yi-Tian Fu, Anson V Koehler, Andreas Hofmann, Bill CH Chang, Shuai Wang, Nan Li, Chu-Yu Lin, Hui Zhang, Lingzi Xiangli, Lin Lin, Wei-Min Liu, Nan Li, Hua-Wei Li, Robin B Gasser, Xing-Quan Zhu

Genomics | Published : 2021

Abstract

Here, we present a draft genome of the tapeworm Dipylidium caninum (family Dipylidiidae) and compare it with other cestode genomes. This draft genome of D. caninum is 110 Mb in size, has a repeat content of ~13.4% and is predicted to encode ~10,000 protein-coding genes. We inferred excretory/secretory molecules (representing the secretome), other key groups of proteins (including peptidases, kinases, phosphatases, GTPases, receptors, transporters and ion-channels) and predicted potential intervention targets for future evaluation. Using 144 shared single-copy orthologous sequences, we investigated the genetic relationships of cestodes for which nuclear genomes are available. This study provi..

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