Journal article

Technical results from a trial of the FREO2 Low-Pressure Oxygen Storage system, Mbarara Regional Referral Hospital, Uganda

David Peake, James Black, Elias Kumbakumba, Sheillah Bagayana, Celestine Barigye, Peter Moschovis, Ivan Muhumuza, Frank Kiwanuka, Patrick Semata, Kevin Rassool, Bryn Sobott, Roger Rassool

PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2021


Increased access to reliable medical oxygen would reduce the global burden of pneumonia. Oxygen concentrators have been shown to be an effective solution, however they have significant drawbacks when used in low-resource environments where pneumonia burden is the heaviest. Low quality grid power can damage oxygen concentrators and blackouts can prevent at-risk patients from receiving continual oxygen therapy. Gaps in prescribed oxygen flow can result in acquired brain injuries, extended hypoxemia and death. The FREO2 Low-Pressure Oxygen Storage (LPOS) system consists of a suite of improvements to a standard oxygen concentrator which address these limitations. This study reports the technical..

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Funding Acknowledgements

FREO<INF>2</INF> Foundation Australia provided support in the form of salaries for authors JB and KR, and funding for the trial including registration costs and nursing support. FREO<INF>2</INF> provided input into the study and product design through their incountry expertise. FREO<INF>2</INF> Foundation assisted in clinical data collection. Data collection and analysis was performed by DP, RR and JB. FREO<INF>2</INF> Foundation operates on philanthropic donations and does not accept commercial funding. Early technical work on the LPOS system was made possible through a Bill and Melinda Gates Foundation Grand Challenges Exploration Phase 1 grant.