A Pan-Canadian Prospective Study of Young Women with Breast Cancer: The Rationale and Protocol Design for the RUBY Study.
ML Quan, IA Olivotto, NN Baxter, CM Friedenreich, K Metcalfe, E Warner, K MacLennan, JE Stephen, MR Akbari, D Howell, S Narod, undefined The Ruby Site Investigators
Current oncology (Toronto, Ont.) | Published : 2020
Introduction: The understanding of the biology and epidemiology of, and the optimal therapeutic strategies for, breast cancer (bca) in younger women is limited. We present the rationale, design, and initial recruitment of Reducing the Burden of Breast Cancer in Young Women (ruby), a unique national prospective cohort study designed to examine the diagnosis, treatment, quality of life, and outcomes from the time of diagnosis for young women with bca. Methods: Over a 4-year period at 33 sites across Canada, the ruby study will use a local and virtual recruitment model to enrol 1200 women with bca who are 40 years of age or younger at the time of diagnosis, before initiation of any treatment. A..View full abstract