Sex differences in fetal Doppler parameters during gestation.
Dakshita Jagota, Hannah George, Melissa Walker, Anjana Ravi Chandran, Natasha Milligan, Shiri Shinar, Clare L Whitehead, Sebastian R Hobson, Lena Serghides, W Tony Parks, Ahmet A Baschat, Christopher K Macgowan, John G Sled, John C Kingdom, Lindsay S Cahill
Biol Sex Differ | Published : 2021
BACKGROUND: Fetal sex is known to affect pregnancy outcomes. In current clinical practice, monitoring of fetal well-being is based on Doppler ultrasound measurements of major placental and fetal vessels. The objective of this study was to investigate the effect of fetal sex on Doppler parameters throughout gestation in healthy pregnancy. METHODS: A prospective study was conducted in 240 pregnant women with ultrasound examinations at a 4-weekly interval between 12 and 38 weeks of gestation. Pulsed Doppler spectra were collected for the umbilical arteries (UAs), middle cerebral artery (MCA), descending abdominal aorta (DAo), and ductus venosus (DV). Linear mixed effects models were used to det..View full abstract