Associations between Bone Material Strength Index, Calcaneal Quantitative Ultrasound, and Bone Mineral Density in Men
Pamela Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Mark A Kotowicz, Julie A Pasco
JOURNAL OF THE ENDOCRINE SOCIETY | ENDOCRINE SOC | Published : 2021
Objectives: Impact micro-indentation (IMI) measures bone material strength index (BMSi) in vivo. This study investigated how IMI is associated with calcaneal quantitative ultrasound and bone densitometry parameters in men. Methods: BMSi was measured on the tibial plateau using the OsteoProbe in 377 men (age 33-96 years) from the Geelong Osteoporosis Study. Broadband ultrasound attenuation (BUA), speed of sound (SOS), and stiffness index (SI) were assessed at the calcaneus using an ultrasonometer. Areal BMD was measured at several skeletal sites using dual-energy x-ray absorptiometry. Linear associations between parameters were tested using Pearson's correlation. Multivariable regression tech..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC)
The Geelong Osteoporosis Study was supported by grants from the National Health and Medical Research Council (NHMRC; projects 299831, 628582), Amgen-GSK OAANZBMS and Amgen Australia, but they played no role in the collection or interpretation of data.