Journal article

Are Sarcopenia and Cognitive Dysfunction Comorbid after Stroke in the Context of Brain-Muscle Crosstalk?

Sophia X Sui, Brenton Hordacre, Julie A Pasco

BIOMEDICINES | MDPI | Published : 2021


Stroke is a leading cause of death and disability and is responsible for a significant economic burden. Sarcopenia and cognitive dysfunction are common consequences of stroke, but there is less awareness of the concurrency of these conditions. In addition, few reviews are available to guide clinicians and researchers on how to approach sarcopenia and cognitive dysfunction as comorbidities after stroke, including how to assess and manage them and implement interventions to improve health outcomes. This review synthesises current knowledge about the relationship between post-stroke sarcopenia and cognitive dysfunction, including the physiological pathways, assessment tools, and interventions i..

View full abstract

University of Melbourne Researchers


Awarded by National Health and Medical Research Council of Australia (NHMRC)

Funding Acknowledgements

S.X.S. was supported by a Deakin Postgraduate Scholarship in conjunction with the Geelong Medical and Hospital Benefits Association (GMHBA) and has been awarded an Executive Dean Health Research Fellowship (Deakin University). BH is supported by a research fellowship from the National Health and Medical Research Council of Australia (NHMRC, 1125054). JAP has received speaker fees from Amgen, Eli Lilly, and Sanofi-Aventis and funding from the NHMRC, Barwon Health, Deakin University, Amgen, the BUPA Foundation, Osteoporosis Australia, the Australian and New Zealand Bone and Mineral Society, the Geelong Community Foundation, Western Alliance, and the Norman Beischer Foundation.