The incidence of acute respiratory infection in Indonesian infants and association with vitamin D deficiency

Vicka Oktaria; Margaret Danchin; Rina Triasih; Yati Soenarto; Julie E Bines; Anne-Louise Ponsonby; Michael W Clarke; Stephen M Graham

Journal article

The incidence of acute respiratory infection in Indonesian infants and association with vitamin D deficiency

Vicka Oktaria, Margaret Danchin, Rina Triasih, Yati Soenarto, Julie E Bines, Anne-Louise Ponsonby, Michael W Clarke, Stephen M Graham

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2021

DOI: 10.1371/journal.pone.0248722

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Abstract

BACKGROUND: Vitamin D deficiency has been associated with acute respiratory infection (ARI) in early life, but this has not been evaluated in Indonesia. We aimed to determine the incidence of ARI in Indonesian infants, and to evaluate the association with vitamin D deficiency. METHODS: From 23 December 2015 to 31 December 2017, we conducted a community-based prospective cohort study in Yogyakarta province. We enrolled 422 pregnant women and followed their infants from birth until 12 months of age for ARI episodes. Vitamin D status was measured at birth and at age six months. We performed Cox proportional hazard regression analysis to evaluate the association between vitamin D deficiency and ..

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University of Melbourne Researchers

Margie Danchin Author Melbourne Medical School

Julie Bines Author Paediatrics Royal Children's Hospital

Stephen Graham Author Paediatrics Royal Children's Hospital

Grants

Awarded by Indonesia Endowment Fund for Education (LPDP) Ministry of Finance

Awarded by Australia-Indonesia Centre (AIC)

Funding Acknowledgements

This study was supported by Murdoch Children's Research Institute in the form of funding awarded to SMG, Schlumberger foundation faculty for the future in the form of funding awarded to VO, Indonesia Endowment Fund for Education (LPDP) Ministry of Finance in the form of a grant awarded to VO (20130822080370), the David Bickart Clinician Research Fellowship from the University of Melbourne awarded to MD, Australia-Indonesia Centre (AIC) in the form of a grant awarded to MD and YS (01HSP1MELDancUGM003), and infrastructure funding from the Western Australian State Government, in partnership with the Australian Federal Government, through Bioplatforms Australia and the National Collaborative Research Infrastructure Strategy awarded to MWC. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.