Journal article

Synchronous Liver Resection, Cytoreductive Surgery, and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Liver and Peritoneal Metastases: A Systematic Review and Meta-analysis

Michael P Flood, Atandrila A Das, Mikael L Soucisse, Joseph Kong, Robert G Ramsay, Michael Michael, Benjamin PT Loveday, Satish K Warrier, Alexander G Heriot

DISEASES OF THE COLON & RECTUM | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

Abstract

BACKGROUND: Synchronous liver resection, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy for colorectal liver and peritoneal metastases have traditionally been contraindicated. More recent clinical practice has begun to promote this aggressive treatment in select patients. OBJECTIVE: This study aimed to investigate the perioperative and oncological outcomes of patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, with and without liver resection, in the management of metastatic colorectal cancer. DATA SOURCES: Medline, Embase, and Cochrane Library databases were searched up to July 2020. STUDY SELECTION: Cohort studies comparing outcome..

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