Journal article

Nonclassical Pathogens as Causative Agents of Proctitis in Men who Have Sex With Men

Eric PF Chow, Darren Lee, Stephanie Bond, Christopher K Fairley, Kate Maddaford, Rebecca Wigan, Glenda Fehler, Sigrid A Lange, Vesna De Petra, Melanie Bissessor, Catriona S Bradshaw, Benjamin P Howden, Jane S Hocking, Deborah A Williamson, Marcus Y Chen



Background: This study aimed to identify enteric and sexually acquired rectal pathogens, other than chlamydia and gonorrhea, associated with symptomatic proctitis in men who have sex with men (MSM). Methods: Anorectal swab samples were obtained from MSM presenting with rectal symptoms and a clinical diagnosis of proctitis at the Melbourne Sexual Health Centre between January 2017 and March 2019. Samples that tested positive for Neisseria gonorrhoeae and Chlamydia trachomatis were excluded. As a comparison group, anorectal samples were also obtained from MSM not reporting symptoms of proctitis between November 2018 and February 2019. Samples from both groups were tested for 15 viral, bacteria..

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Awarded by National Health and Medical Research Council

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

This study was supported by SpeeDx and a Project Grant from the National Health and Medical Research Council (GNT1147735, D.A.W., M.Y.C., E.P.F.C., C.K.F.). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. E.P.F.C. and D.A.W. are supported by Australian National Health and Medical Research Council (NHMRC) Emerging Leadership Investigator Grants (GNT1172873 and GNT1174555, respectively). C.K.F. and C.S.B. are supported by NHMRC Leadership Investigator Grants (GNT1172900 and GNT1173361, respectively). B.P.H. is supported by an NHMRC Practitioner Fellowship (GNT1105905). J.S.H. is supported by an NHMRC Senior Research Fellowship (GNT1136117).