Prevalence and clinical correlates of insomnia symptoms and their association with quality of life in Chinese patients with HBV-related liver disease

Jing Zhao; Mei Liu; Gabor S Ungvari; Chee H Ng; Ines Hang Iao Chow; Ting Wang; Yu Chen; Zhongping Duan; Yu-Tao Xiang; Su-Jun Zheng

Journal article

Prevalence and clinical correlates of insomnia symptoms and their association with quality of life in Chinese patients with HBV-related liver disease

Jing Zhao, Mei Liu, Gabor S Ungvari, Chee H Ng, Ines Hang Iao Chow, Ting Wang, Yu Chen, Zhongping Duan, Yu-Tao Xiang, Su-Jun Zheng

PEERJ | PEERJ INC | Published : 2021

DOI: 10.7717/peerj.10956

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Abstract

Objective: This study aimed to describe the one-month prevalence of insomnia symptoms (insomnia hereafter) and the demographic and clinical correlates, and its association with quality of life (QOL) in Chinese patients with HBV-related liver disease. Method: A total of 689 patients with HBV-related liver disease in Beijing, China formed the study sample. Three forms of insomnia including difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS) and early morning awakening (EMA) were assessed using standardized questions. QOL was measured using the Medical Outcomes Study Short Form 12 (SF-12). Results: The one-month prevalence of at least one type of insomnia was 69.5%, while DIS,..

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University of Melbourne Researchers

Chee Ng Author Psychiatry

Grants

Awarded by Beijing Municipal Administration of Hospitals Clinical medicine Development of special funding support

Awarded by Beijing Health System

Awarded by Scientific Research Common Program of Beijing Municipal Commission of Education

Awarded by National Science and Technology Key Project

Funding Acknowledgements

This work was supported by Beijing Municipal Administration of Hospitals Clinical medicine Development of special funding support (XMLX201830, ZYLX202125). Grant of High technical personnel training item from Beijing Health System (2015-3-104); Scientific Research Common Program of Beijing Municipal Commission of Education (KM201610025021); National Science and Technology Key Project on ``Major Infectious Diseases such as HIV/AIDS, Viral Hepatitis Prevention and Treatment'' (2017ZX10202203006, 2017ZX10302201-004). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.