Book Chapter
The Dual Specificity of Virus-Immune T Cells
Peter C Doherty, Jack R Bennink, Rita B Effros, Mark Frankel
Current Trends in Histocompatibility | Springer US | Published : 1981
Abstract
A current obsession of cellular immunology is the definition of the T-cell receptor repertoire. Many of the questions that have been raised derive from experiments with virus systems (Doherty et al., 1976a; Zinkernagel and Doherty, 1979). How do we explain the apparent dual specificity for major histocompatibility (MHC) components and for virus?