Journal article

Management of Arrhythmias After Heart Transplant: Current State and Considerations for Future Research.

Jose A Joglar, Elaine Y Wan, Mina K Chung, Alejandra Gutierrez, Mark S Slaughter, Brian P Bateson, Michael Loguidice, Mark Drazner, Peter M Kistler, Basil Saour, Jeanne E Poole, Ghulam Murtaza, Mohit K Turagam, Justin Vader, Dhanunjaya Lakkireddy, Edo Y Birati, Ravi Dhingra, Rakesh Gopinathannair

Circulation Arrhythmia and Electrophysiology | Published : 2021


Orthotropic heart transplantation remains the most effective therapy for patients with end-stage heart failure, with a median survival of ≈13 years. Yet, a number of complications are observed after orthotropic heart transplantation, including atrial and ventricular arrhythmias. Several factors contribute to arrhythmias, such as autonomic denervation, effect of the surgical technique, acute and chronic rejection, and transplant vasculopathy among others. To minimize risk of future arrhythmias, the bicaval technique and minimizing ischemic time are current surgical standards. Sinus node dysfunction is the most common indication for early (within 30 days) pacemaker implantation, whereas atriov..

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