Journal article

Genomic Hotspots for Adaptation: The Population Genetics of Mullerian Mimicry in Heliconius erato

Brian A Counterman, Felix Araujo-Perez, Heather M Hines, Simon W Baxter, Clay M Morrison, Daniel P Lindstrom, Riccardo Papa, Laura Ferguson, Mathieu Joron, Richard H Ffrench-Constant, Christopher P Smith, Dahlia M Nielsen, Rui Chen, Chris D Jiggins, Robert D Reed, Georg Halder, Jim Mallet, W Owen McMillan



Wing pattern evolution in Heliconius butterflies provides some of the most striking examples of adaptation by natural selection. The genes controlling pattern variation are classic examples of Mendelian loci of large effect, where allelic variation causes large and discrete phenotypic changes and is responsible for both convergent and highly divergent wing pattern evolution across the genus. We characterize nucleotide variation, genotype-by-phenotype associations, linkage disequilibrium (LD), and candidate gene expression patterns across two unlinked genomic intervals that control yellow and red wing pattern variation among mimetic forms of Heliconius erato. Despite very strong natural selec..

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University of Melbourne Researchers


Awarded by National Science Foundation

Awarded by BBSRC

Awarded by Biotechnology and Biological Sciences Research Council

Funding Acknowledgements

Funding for this study was provided by National Science Foundation grants to WOM (DEB-0715096 and IBN-0344705) and BAC (DEB-0513424). Funding for work on H. melpomene came from a BBSRC grant to CDJ and RHf-C (011845). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.