Journal article
Parallel evolution of Bacillus thuringiensis Toxin Resistance in Lepidoptera
SW Baxter, FR Badenes-Pérez, A Morrison, H Vogel, N Crickmore, W Kain, P Wang, DG Heckel, CD Jiggins
Genetics | GENETICS SOC AM | Published : 2011
Abstract
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function. © 2011 by the Genetics Society of America.
Grants
Awarded by Biotechnology and Biological Sciences Research Council
Funding Acknowledgements
We thank Bruce Tabashnik and an anonymous reviewer for helpful comments on this manuscript. This work was funded by the Biotechnology and Biological Sciences Research Council (grant 021107), the Max-Planck-Gesellschaft, and the U.S. Department of Agriculture (grant 2008-35302-18806).