Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera.
Simon W Baxter, Francisco R Badenes-Pérez, Anna Morrison, Heiko Vogel, Neil Crickmore, Wendy Kain, Ping Wang, David G Heckel, Chris D Jiggins
Genetics | Published : 2011
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
Awarded by Biotechnology and Biological Sciences Research Council