Journal article

Mis-Spliced Transcripts of Nicotinic Acetylcholine Receptor alpha 6 Are Associated with Field Evolved Spinosad Resistance in Plutella xylostella (L.)

Simon W Baxter, Mao Chen, Anna Dawson, Jian-Zhou Zhao, Heiko Vogel, Anthony M Shelton, David G Heckel, Chris D Jiggins

PLOS GENETICS | PUBLIC LIBRARY SCIENCE | Published : 2010

Abstract

The evolution of insecticide resistance is a global constraint to agricultural production. Spinosad is a new, low-environmental-risk insecticide that primarily targets nicotinic acetylcholine receptors (nAChR) and is effective against a wide range of pest species. However, after only a few years of application, field evolved resistance emerged in the diamondback moth, Plutella xylostella, an important pest of brassica crops worldwide. Spinosad resistance in a Hawaiian population results from a single incompletely recessive and autosomal gene, and here we use AFLP linkage mapping to identify the chromosome controlling resistance in a backcross family. Recombinational mapping with more than 70..

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University of Melbourne Researchers