The clinical features that contribute to poor bone health in young Australians living with cystic fibrosis: A recommendation for BMD screening

Abstract

Background: For Australians living with cystic fibrosis (CF), increased longevity means greater consideration needs to be given to long-term endocrine sequelae such as CF-related bone disease. Deficits in bone mass accrual are most likely to occur during childhood and adolescence. Current guidelines in Australia suggest repeat dual-energy X-ray absorptiometry (DXA) scans every 2 years. This study aims to stratify clinical factors that determine future bone health in the Australian CF population and use this to guide a more streamlined approach to bone health screening. Methods: This study was a retrospective audit of all patients diagnosed with CF who were treated at the Royal Children's Hos..