Journal article
International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery
AG Lindgren, RG Braun, J Juhl Majersik, P Clatworthy, S Mainali, CP Derdeyn, J Maguire, C Jern, J Rosand, JW Cole, JM Lee, P Khatri, P Nyquist, S Debette, L Keat Wei, T Rundek, D Leifer, V Thijs, R Lemmens, L Heitsch Show all
International Journal of Stroke | Published : 2022
Abstract
Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. Large sample sizes are needed to detect commonly occurring genetic variations related to stroke brain injury and recovery. However, this usually requires combining data from multiple studies where consistent terminology, methodology, and data collection timelines are essential. Our group of expert stroke and rehabilitation clinicians and researchers with knowledge in genetics of stroke recovery here present recommendati..
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Awarded by National Institutes of Health
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by National Institute of Child Health and Human Development (K12HD093427); Lund University; National Institute of Neurological Disorders and Stroke (K23NS099487-01, R01-NS082285, R01-NS086905, U19-NS115388 and 5U10NS086606); National Institutes of Health (KL2TR003016, R01NS085419, R01-NS100178, R01-NS105150, R01-NS114045, R21-NS106480, U24-NS107230, U24-NS107237 and U24NS107222); Maestro Project and Ibiostroke project funded by Eranet-Neuron, ISCIII and FEDER; CaNVAS project funded by National Institutes of Health; Department of Biotechnology, Ministry of Science and Technology, India; Skane University Hospital; Region Skne; The Swedish Heart and Lung Foundation; and The Swedish Research Council (2018-02543 and 2019-01757); The Swedish Government (under the "Avtal om Lakarutbildning och Medicinsk Forskning, ALF''); Sparbanksstiftelsen Fars och Frosta; Freemason's Lodge of Instruction Eos, Lund; FWO Flanders (1841918N); US Department of Veteran Affairs, the American Heart Association (15GPSG23770000, 17IBDG3300328).