Field Effect Biosensing Platform Based on 2D alpha-MoO3
Sivacarendran Balendhran, Sumeet Walia, Manal Alsaif, Emily P Nguyen, Jian Zhen Ou, Serge Zhuiykov, Sharath Sriram, Madhu Bhaskaran, Kourosh Kalantar-zadeh
ACS Nano | AMER CHEMICAL SOC | Published : 2013
Electrical-based biosensing platforms offer ease of fabrication and simple sensing solutions. Recently, two-dimensional (2D) semiconductors have been proven to be excellent for the fabrication of field effect transistors (FETs) due to their large transconductance, which can be efficiently used for developing sensitive bioplatforms. We present a 2D molybdenum trioxide (MoO3) FET based biosensing platform, using bovine serum albumin as a model protein. The conduction channel is a nanostructured film made of 2D α-MoO3 nanoflakes, with the majority of nanoflake thicknesses being equal to or less than 2.8 nm. The response time is impressively low (less than 10 s), which is due to the high permitt..View full abstract
Awarded by Australian Research Council
S.S. and M.B. acknowledge the Australian Post-Doctoral Fellowships from the Australian Research Council through Discovery Projects DP110100262 and DP1092717, respectively. S.S. and K.K.Z. acknowledge the Australian Research Council for equipment funding through the Linkage, Infrastructure, Equipment, and Facilities Grant LE100100215. S.B. acknowledges a publication grant from the School of Graduate Research at RMIT University. The work was partially supported by the CSIRO Sensors and Sensor Networks Transformational Capability Platform (SSN TCP) and CSIRO Materials Science and Engineering Division (CMSE). The authors also would like to acknowledge the facilities and technical assistance of the Australian Microscopy& Microanalysis Research Facility at the RMIT Microscopy & Microanalysis Facility, at RMIT University.