Journal article
Prognosis of Severe Low-Flow, Low-Gradient Aortic Stenosis by Stroke Volume Index and Transvalvular Flow Rate
J Sen, Q Huynh, D Stub, C Neil, TH Marwick
Jacc Cardiovascular Imaging | Published : 2021
Abstract
Objectives: This study determined whether flow state classified by stroke volume index (SVi) or transvalvular flow rate (FR) improved risk stratification of all-cause mortality, hospitalization due to heart failure, and aortic valvular interventions for patients with severe aortic stenosis (AS). Background: SVi is a widely accepted classification for flow state in severe low-flow, low-gradient (LFLG) AS. Recent studies suggest that FR more closely approximates true AS severity and provides more useful prognostication than SVi. Methods: Patients with severe AS over a 7-year period were subclassified by echocardiographic parameters. LFLG-AS was defined as severe AS (aortic valve area index [AV..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work has been supported in part by a partnership grant (1149692) from the National Health and Medical Research Council, Canberra. Dr. Sen was supported by scholarships from the National Heart Foundation of Australia (identification: 102578) , National Health and Medical Research Council of Australia (identification: 1191044) , Baker Heart and Diabetes Institute (Bright Sparks) , and the Australian Government Research Training Program. Dr. Stub is supported by a fellowship from the National Heart Foundation, Canberra. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.