Fibrinogen, collagen, and transferrin adsorption to poly(3,4-ethylenedioxythiophene)-xylorhamno-uronic glycan composite conducting polymer biomaterials for wound healing applications
Paul J Molino, John Will, Luciana Yumiko Daikuara, Alexander R Harris, Zhilian Yue, Jeremy Dinoro, Pia Winberg, Gordon G Wallace
Biointerphases: an open access journal for the biomaterials interface community | AIP Publishing LLC | Published : 2021
We present the conducting polymer poly (3,4-ethylenedioxythiophene) (PEDOT) doped with an algal-derived glycan extract, Phycotrix™ [xylorhamno-uronic glycan (XRU84)], as an innovative electrically conductive material capable of providing beneficial biological and electrical cues for the promotion of favorable wound healing processes. Increased loading of the algal XRU84 into PEDOT resulted in a reduced surface nanoroughness and interfacial surface area and an increased static water contact angle. PEDOT-XRU84 films demonstrated good electrical stability and charge storage capacity and a reduced impedance relative to the control gold electrode. A quartz crystal microbalance with dissipation mo..View full abstract
Awarded by Australian Research Council (ARC) through the Australian Centre of Excellence for Electromaterials Science
The authors gratefully acknowledge funding from the Australian Research Council (ARC) through the Australian Centre of Excellence for Electromaterials Science (CE140100012). We also thank the Australian National Fabrication Facility for providing access to equipment.