Journal article

Vitamin D as A Protector of Arterial Health: Potential Role in Peripheral Arterial Disease Formation

Smriti Murali Krishna

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | MDPI | Published : 2019

Abstract

Atherosclerotic occlusive diseases and aneurysms that affect large and medium-sized arteries outside the cardiac and cerebral circulation are collectively known as peripheral arterial disease (PAD). With a rise in the rate of aging population worldwide, the number of people diagnosed with PAD is rapidly increasing. The micronutrient vitamin D is an important steroid hormone that acts on many crucial cellular mechanisms. Experimental studies suggest that optimal levels of vitamin D have beneficial effects on the heart and blood vessels; however, high vitamin D concentrations have been implicated in promoting vascular calcification and arterial stiffness. Observations from various clinical stu..

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