Vitamin D as A Protector of Arterial Health: Potential Role in Peripheral Arterial Disease Formation
Smriti Murali Krishna
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | MDPI | Published : 2019
Atherosclerotic occlusive diseases and aneurysms that affect large and medium-sized arteries outside the cardiac and cerebral circulation are collectively known as peripheral arterial disease (PAD). With a rise in the rate of aging population worldwide, the number of people diagnosed with PAD is rapidly increasing. The micronutrient vitamin D is an important steroid hormone that acts on many crucial cellular mechanisms. Experimental studies suggest that optimal levels of vitamin D have beneficial effects on the heart and blood vessels; however, high vitamin D concentrations have been implicated in promoting vascular calcification and arterial stiffness. Observations from various clinical stu..View full abstract
Awarded by College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia
This research was supported by the Research Capacity Building Funding (RCB: JCU-QLD-932377) from College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.