Journal article

Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China

Zhi-Zhou He, Peng-Yue Guo, Shu-Li Xu, Yang Zhou, Bin Jalaludin, Ari Leskinen, Luke D Knibbs, Joachim Heinrich, Lidia Morawska, Steve Hung-Lam Yim, Dinh Bui, Mika Komppula, Marjut Roponen, Liwen Hu, Gongbo Chen, Xiao-Wen Zeng, Yunjiang Yu, Bo-Yi Yang, Guanghui Dong

ENVIRONMENTAL SCIENCE & TECHNOLOGY | AMER CHEMICAL SOC | Published : 2021

Abstract

Existing evidence is scarce concerning the various effects of different PM sizes and chemical constituents on blood lipids. A panel study that involved 88 healthy college students with five repeated measurements (440 blood samples in total) was performed. We measured mass concentrations of particulate matter with diameters ≤ 2.5 μm (PM2.5), ≤1.0 μm (PM1.0), and ≤0.5 μm (PM0.5) as well as number concentrations of particulate matter with diameters ≤ 0.2 μm (PN0.2) and ≤0.1 μm (PN0.1). We applied linear mixed-effect models to assess the associations between short-term exposure to different PM size fractions and PM2.5 constituents and seven lipid metrics. We found significant associations of gre..

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Grants

Awarded by National Natural Science Foundation of China


Awarded by Science and Technology Program of Guangzhou


Awarded by National Key Research and Development Program of China


Awarded by Guangdong Provincial Natural Science Foundation Team Project


Awarded by Fundamental Research Funds for the Central Universities


Awarded by Natural Science Foundation of Guangdong Province


Funding Acknowledgements

This work was supported by the National Natural Science Foundation of China (81703179, 81673128, 81950410633, 81972992, 81872582, 81872583), the Science and Technology Program of Guangzhou (201807010032, 201803010054), the National Key Research and Development Program of China (2018YFC1004300, 2018YFE0106900), the Guangdong Provincial Natural Science Foundation Team Project (2018B030312005), the Fundamental Research Funds for the Central Universities (19ykjc01), and the Natural Science Foundation of Guangdong Province (2020A1515011131, 2019A050510017, 2018B05052007, 2017A090905042, 2020A1515011167).