Journal article
Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China
Zhi-Zhou He, Peng-Yue Guo, Shu-Li Xu, Yang Zhou, Bin Jalaludin, Ari Leskinen, Luke D Knibbs, Joachim Heinrich, Lidia Morawska, Steve Hung-Lam Yim, Dinh Bui, Mika Komppula, Marjut Roponen, Liwen Hu, Gongbo Chen, Xiao-Wen Zeng, Yunjiang Yu, Bo-Yi Yang, Guanghui Dong
ENVIRONMENTAL SCIENCE & TECHNOLOGY | AMER CHEMICAL SOC | Published : 2021
Abstract
Existing evidence is scarce concerning the various effects of different PM sizes and chemical constituents on blood lipids. A panel study that involved 88 healthy college students with five repeated measurements (440 blood samples in total) was performed. We measured mass concentrations of particulate matter with diameters ≤ 2.5 μm (PM2.5), ≤1.0 μm (PM1.0), and ≤0.5 μm (PM0.5) as well as number concentrations of particulate matter with diameters ≤ 0.2 μm (PN0.2) and ≤0.1 μm (PN0.1). We applied linear mixed-effect models to assess the associations between short-term exposure to different PM size fractions and PM2.5 constituents and seven lipid metrics. We found significant associations of gre..
View full abstractGrants
Awarded by National Natural Science Foundation of China
Awarded by Science and Technology Program of Guangzhou
Awarded by National Key Research and Development Program of China
Awarded by Guangdong Provincial Natural Science Foundation Team Project
Awarded by Fundamental Research Funds for the Central Universities
Awarded by Natural Science Foundation of Guangdong Province
Funding Acknowledgements
This work was supported by the National Natural Science Foundation of China (81703179, 81673128, 81950410633, 81972992, 81872582, 81872583), the Science and Technology Program of Guangzhou (201807010032, 201803010054), the National Key Research and Development Program of China (2018YFC1004300, 2018YFE0106900), the Guangdong Provincial Natural Science Foundation Team Project (2018B030312005), the Fundamental Research Funds for the Central Universities (19ykjc01), and the Natural Science Foundation of Guangdong Province (2020A1515011131, 2019A050510017, 2018B05052007, 2017A090905042, 2020A1515011167).