Journal article

Associations Between Neighborhood Disadvantage, Resting-State Functional Connectivity, and Behavior in the Adolescent Brain Cognitive Development Study: The Moderating Role of Positive Family and School Environments

Divyangana Rakesh, Caio Seguin, Andrew Zalesky, Vanessa Cropley, Sarah Whittle

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING | ELSEVIER | Published : 2021

Abstract

BACKGROUND: Neighborhood disadvantage has consistently been associated with mental health and cognitive function, in addition to alterations in brain function and connectivity. However, positive environmental influences may buffer these effects. The aim of this study was to examine the association between neighborhood disadvantage and resting-state functional connectivity (rsFC), the moderating role of positive parenting and school environment, and relationships between disadvantage-associated rsFC patterns and mental health and cognition. METHODS: In this preregistered study, we tested this hypothesis in a large sample of 7618 children (aged 9-10 years) from the Adolescent Brain Cognitive D..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC Senior Research Fellowship


Awarded by NHMRC Career Development Fellowship


Funding Acknowledgements

This work was supported by Melbourne Research Scholarship ([to DR]), National Health and Medical Research Council (NHMRC) (Grant No. 1177370 [to VC]), NHMRC Senior Research Fellowship (Grant No. 1136649 [to AZ]), and NHMRC Career Development Fellowship (Grant No. 1125504 [to SW]). This manuscript reflects the views of the authors and may not reflect the opinions or views of the National Institutes of Health or ABCD consortium investigators.