Toward a Systematic Nomenclature for (Neo)Lignanamides
Annemiek van Zadelhoff, Wouter JC de Bruijn, Zhongxiang Fang, Emmanuel Gaquerel, Atsushi Ishihara, Daniele Werck-Reichhart, Pangzhen Zhang, Guangxiong Zhou, Maurice CR Franssen, Jean-Paul Vincken
JOURNAL OF NATURAL PRODUCTS | AMER CHEMICAL SOC | Published : 2021
Phenylalkenoic acid amides, often referred to as phenol amides or hydroxycinnamic acid amides, are bioactive phytochemicals, whose bioactivity can be enhanced by coupling to form dimers or oligomers. Phenylalkenoic acid amides consist of a (hydroxy)cinnamic acid derivative (i.e., the phenylalkenoic acid subunit) linked to an amine-containing compound (i.e., the amine subunit) via an amide bond. The phenylalkenoic acid moiety can undergo oxidative coupling, either catalyzed by oxidative enzymes or due to autoxidation, which leads to the formation of (neo)lignanamides. Dimers described in the literature are often named after the species in which the compound was first discovered; however, the ..View full abstract
Awarded by Netherlands Organisation for Scientific Research (NWO) by an NWO Graduate School Green Top Sectors grant
This research received funding from The Netherlands Organisation for Scientific Research (NWO) by an NWO Graduate School Green Top Sectors grant (GSGT.2019.004).