Journal article

Predictors of New-Onset Epilepsy in People With Younger-Onset Neurocognitive Disorders

Xinshi Wang, Samantha M Loi, Emma Foster, Zhibin Chen, Dennis Velakoulis, Patrick Kwan

FRONTIERS IN AGING NEUROSCIENCE | FRONTIERS MEDIA SA | Published : 2021

Abstract

Objective: People with neurocognitive disorders (NCDs) have an increased risk of epilepsy. However, most studies investigating the risk of seizures in people with NCDs are limited to those with Alzheimer's disease (AD) and vascular dementia (VD), and those who developed dementia after age 65 years. A knowledge gap exists regarding factors associated with development of epilepsy in people with younger-onset NCD, and those with non-AD and non-VD dementia subtypes. In this study, we aimed to identify the factors associated with the development of epilepsy in people with younger-onset NCDs of varied etiologies, the majority of whom had symptom onset prior to age 65 years. Participants and Method..

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Grants

Awarded by Chinese Scholarship Council


Awarded by National Natural Science Foundation of China


Funding Acknowledgements

This study was supported by the Chinese Scholarship Council Grant (201808330160) and the National Natural Science Foundation of China (82001363).