Combination of Quantitative MRI Fat Fraction and Texture Analysis to Evaluate Spastic Muscles of Children With Cerebral Palsy
Tugba Akinci D'Antonoli, Francesco Santini, Xeni Deligianni, Meritxell Garcia Alzamora, Erich Rutz, Oliver Bieri, Reinald Brunner, Claudia Weidensteiner
FRONTIERS IN NEUROLOGY | FRONTIERS MEDIA SA | Published : 2021
Background: Cerebral palsy (CP) is the most common cause of physical disability in childhood. Muscle pathologies occur due to spasticity and contractures; therefore, diagnostic imaging to detect pathologies is often required. Imaging has been used to assess torsion or estimate muscle volume, but additional methods for characterizing muscle composition have not thoroughly been investigated. MRI fat fraction (FF) measurement can quantify muscle fat and is often a part of standard imaging in neuromuscular dystrophies. To date, FF has been used to quantify muscle fat and assess function in CP. In this study, we aimed to utilize a radiomics and FF analysis along with the combination of both metho..View full abstract
Awarded by Swiss National Science Foundation
This study was supported by the Swiss National Science Foundation (Grant No. 173292).