Early Moves: a protocol for a population-based prospective cohort study to establish general movements as an early biomarker of cognitive impairment in infants
Catherine Elliott, Caroline Alexander, Alison Salt, Alicia J Spittle, Roslyn N Boyd, Nadia Badawi, Catherine Morgan, Desiree Silva, Elizabeth Geelhoed, Robert S Ware, Alishum Ali, Anne McKenzie, David Bloom, Mary Sharp, Roslyn Ward, Samudragupta Bora, Susan Prescott, Susan Woolfenden, Vuong Le, Sue-Anne Davidson Show all
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2021
INTRODUCTION: The current diagnostic pathways for cognitive impairment rarely identify babies at risk before 2 years of age. Very early detection and timely targeted intervention has potential to improve outcomes for these children and support them to reach their full life potential. Early Moves aims to identify early biomarkers, including general movements (GMs), for babies at risk of cognitive impairment, allowing early intervention within critical developmental windows to enable these children to have the best possible start to life. METHOD AND ANALYSIS: Early Moves is a double-masked prospective cohort study that will recruit 3000 term and preterm babies from a secondary care setting. Ea..View full abstract
Supported by a Clinical Trials and Cohort Study Grant awarded by the National Health and Medical Research Council, a Project Grant awarded by the Research Foundation, Cerebral Palsy Alliance, a Project Grant awarded by the WA Child Research Foundation and a Project Grant awarded by the Perth Children's Hospital Foundation.