A systematic review and meta-analysis of the effect of routine early angiography in patients with return of spontaneous circulation after Out-of-Hospital Cardiac Arrest.

Nikolaos I Nikolaou; Stuart Netherton; Michelle Welsford; Ian R Drennan; Kevin Nation; Emilie Belley-Cote; Nazi Torabi; Laurie J Morrison; International Liaison Committee on Resuscitation Advanced Life Support Task Force (ILCOR)

Journal article

A systematic review and meta-analysis of the effect of routine early angiography in patients with return of spontaneous circulation after Out-of-Hospital Cardiac Arrest.

Nikolaos I Nikolaou, Stuart Netherton, Michelle Welsford, Ian R Drennan, Kevin Nation, Emilie Belley-Cote, Nazi Torabi, Laurie J Morrison, undefined International Liaison Committee on Resuscitation Advanced Life Support Task Force (ILCOR)

Resuscitation | Elsevier BV | Published : 2021

DOI: 10.1016/j.resuscitation.2021.03.019

Abstract

BACKGROUND: Early coronary angiography (CAG) has been reported in individual studies and systematic reviews to significantly improve outcomes of patients with return of spontaneous circulation (ROSC) after cardiac arrest (CA). METHODS: We undertook a systematic review and meta-analysis to evaluate the impact of early CAG on key clinical outcomes in comatose patients after ROSC following out-of-hospital CA of presumed cardiac origin. We searched the PubMED, EMBASE, CINAHL, ERIC and Cochrane Central Register of Controlled Trials databases from 1990 until April 2020. Eligible studies compared patients undergoing early CAG to patients with late or no CAG. When randomized controlled trials (RCTs)..

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