Journal article

Non-small cell lung cancer stage migration as a function of wait times from diagnostic imaging: A pooled analysis from five international centres

Jean-Pierre Bissonnette, Alexander Sun, Inga S Grills, Muayad F Almahariq, Geoffrey Geiger, Wouter Vogel, Jan-Jakob Sonke, Sarah Everitt, Michael Mac Manus

LUNG CANCER | ELSEVIER IRELAND LTD | Published : 2021

Abstract

INTRODUCTION: Patients with non-small cell lung cancer (NSCLC) can experience rapid disease progression between initial staging FDG-PET scans and commencement of curative-intent radiotherapy (RT). Previous studies that estimated stage migration rates by comparing staging PET/CT and treatment-planning PET/CT images were limited by small sample sizes. METHODS: This multicenter, international study combined prospective data from five institutions for PET-staged patients with NSCLC who were intended to receive curative-intent RT. TNM status was compared for staging and RT planning scans and the probability of TNM status and overall stage migration was analyzed as a function of the interval betwe..

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