The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain

Abstract

Objective: To assess the analgesic efficacy and safety of single-dose oral cannabidiol (CBD) as an adjunct to standard care for patients presenting to an emergency department with acute low back pain. Design: Randomised, double blinded, placebo-controlled clinical trial. Setting: The tertiary emergency department of Austin Hospital, Melbourne. Participants: Patients who presented with acute, non-traumatic low back pain between 21 May 2018 and 13 June 2019. Intervention: One hundred eligible patients were randomised to receiving 400 mg CBD or placebo in addition to standard emergency department analgesic medication. Main outcome measures: Pain score two hours after administration of study age..