Journal article
Targeting I/R Injury: A Self‐Assembled Fluorescent Nanoprobe for Imaging and Therapy of Cardiac Ischemia/Reperfusion Injury (Adv. Therap. 3/2019)
Melanie Ziegler, Xiaoqiu Xu, May Lin Yap, Houyuan Hu, Jianxiang Zhang, Karlheinz Peter
Advanced Therapeutics | Wiley | Published : 2019
Abstract
Nanoparticles are an attractive means for molecular imaging and targeted delivery of therapeutics. In article number adtp.201800133 Jianxiang Zhang, Karlheinz Peter and co‐workers synthesize and characterize the functionality of a self‐assembled, ROS‐responsive fluorescent nanoprobe. Using in vivo mouse studies, the authors demonstrate the feasibility and great potential of these nanoparticles as a tool for diagnostic and therapeutic targeting of cardiac tissue undergoing ischemia/reperfusion injury.