Conference Proceedings

Adjuvant chemotherapy (AC) choices: An analysis of elderly Australian patients with stage III colorectal cancer (CRC)

Oliver Piercey, Clara Leung, Margaret Lee, Jeanne Tie, Justin Yeung, Jacob McCormick, Malcolm Steel, Valerie Heong, Yat Hang To, Peter Gibbs, Rachel Wong, Hui-Li Wong

JOURNAL OF CLINICAL ONCOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

Abstract

16 Background: The optimal adjuvant treatment regimen for stage III CRC patients aged ≥70 years remains unclear. Subgroup analyses of randomised trials support the use of single agent fluoropyrimidines (FP) but no survival benefit has been observed for the addition of oxaliplatin. This study assessed rates of AC use in elderly patients with stage III CRC, analysed reasons why elderly patients did not receive AC and compared disease free survival (DFS) between those who did and did not receive AC. Methods: Data was analysed from the ACCORD-CRC registry, which prospectively collects treatment and outcome data from patients with CRC in Australia. All patients aged ≥70 years with resected stage..

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