Journal article

Functional Femtoliter Droplets for Ultrafast Nanoextraction and Supersensitive Online Microanalysis

Miaosi Li, Brendan Dyett, Haitao Yu, Vipul Bansal, Xuehua Zhang

SMALL | WILEY-V C H VERLAG GMBH | Published : 2019

Abstract

A universal femtoliter surface droplet-based platform for direct quantification of trace of hydrophobic compounds in aqueous solutions is presented. Formation and functionalization of femtoliter droplets, concentrating the analyte in the solution, are integrated into a simple fluidic chamber, taking advantage of the long-term stability, large surface-to-volume ratio, and tunable chemical composition of these droplets. In situ quantification of the extracted analytes is achieved by surface-enhanced Raman scattering (SERS) spectroscopy by nanoparticles on the functionalized droplets. Optimized extraction efficiency and SERS enhancement by tuning droplet composition enable quantitative determin..

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University of Melbourne Researchers