Functional Femtoliter Droplets for Ultrafast Nanoextraction and Supersensitive Online Microanalysis
Miaosi Li, Brendan Dyett, Haitao Yu, Vipul Bansal, Xuehua Zhang
SMALL | WILEY-V C H VERLAG GMBH | Published : 2019
A universal femtoliter surface droplet-based platform for direct quantification of trace of hydrophobic compounds in aqueous solutions is presented. Formation and functionalization of femtoliter droplets, concentrating the analyte in the solution, are integrated into a simple fluidic chamber, taking advantage of the long-term stability, large surface-to-volume ratio, and tunable chemical composition of these droplets. In situ quantification of the extracted analytes is achieved by surface-enhanced Raman scattering (SERS) spectroscopy by nanoparticles on the functionalized droplets. Optimized extraction efficiency and SERS enhancement by tuning droplet composition enable quantitative determin..View full abstract
Related Projects (1)
Awarded by Australian Research Council
The authors acknowledge the funding support from the Australian Research Council through Future Fellowships (FT120100473 - X.Z., FT140101285 - V.B.), Micro Nano Research Facility (MNRF), Microscopy and Microanalysis Facility (RMMF) and Sir Ian Potter NanoBioSensing Facility at RMIT University. M.L. also acknowledges the Vice-Chancellor Postdoctoral Fellowship from RMIT University.