Conference Proceedings
Association between global longitudinal strain and cardiopulmonary fitness in patients with breast cancer
A Bonsignore, E Amir, TH Marwick, B Thampinathan, C Brezden-Masley, K Yared, Y Thevakumaran, BJ Wintersperger, P Thavendiranathan
EUROPEAN HEART JOURNAL | OXFORD UNIV PRESS | Published : 2020
Abstract
Abstract Background Anthracycline and trastuzumab therapies improve survival in the cancer population, but are limited by treatment induced cardiotoxicity. Echocardiography derived global longitudinal strain (GLS) permits more sensitive detection of cardiotoxicity than left ventricular ejection fraction (LVEF). However, the clinical implication of a reduction in GLS in cancer survivors is unknown. Purpose To define the association between GLS and cardiopulmonary fitness in women with breast cancer immediately post cancer therapy. ..
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Funding Acknowledgements
Type of funding source: Public grant(s) - National budget only. Main funding source(s): Canadian Institute of Health Research