Journal article

Cognitive Bias Modification for paranoia (CBM-pa): study protocol for a randomised controlled trial

Jenny Yiend, Antonella Trotta, Christopher Meek, Ilvana Dzafic, Nora Baldus, Bryony Crane, Thomas Kabir, Daniel Stahl, Margaret Heslin, Sukhwinder Shergill, Philip McGuire, Emmanuelle Peters

TRIALS | BIOMED CENTRAL LTD | Published : 2017

Abstract

BACKGROUND: Persecutory delusions are the most common type of delusions in psychosis and present in around 10-15% of the general population. Persecutory delusions are thought to be sustained by biased cognitive and emotional processes. Recent advances favour targeted interventions, focussing on specific symptoms or mechanisms. Our aim is to test the clinical feasibility of a novel psychological intervention, which manipulates biased interpretations toward more adaptive processing, in order to reduce paranoia in patients. METHODS: The 'Cognitive Bias Modification for paranoia' (CBM-pa) study is a feasibility, double-blind, randomised controlled trial (RCT) for 60 stabilised outpatients with p..

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Grants

Awarded by National Institute for Health Research (NIHR)/Wellcome Trust King's Clinical Research Facility


Awarded by Medical Research Council


Awarded by National Institute for Health Research


Funding Acknowledgements

This study represents independent research supported by the National Institute for Health Research (NIHR)/Wellcome Trust King's Clinical Research Facility (Research for Patient Benefit reference: PB-PG-0214-33007), and the NIHR Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust. The funding source provided only financial support for the conduct of the research.The research was funded in part by the NIHR Clinical Research Network (CRN). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.