Correlation of Vaccine Responses
Petra Zimmermann, Nicole Ritz, Kirsten P Perrett, Nicole L Messina, Fiona RM van der Klis, Nigel Curtis
FRONTIERS IN IMMUNOLOGY | FRONTIERS MEDIA SA | Published : 2021
Introduction: The humoral response to vaccinations varies widely between individuals. There is no data available on the correlation between responses to different vaccines. In this study, we investigated the correlation of antibody responses between routine vaccine antigens in infants. Methods: One and seven months after the 6-month vaccinations and one month after the 12-month vaccinations, antibody concentrations to diphtheria, tetanus, pertussis, polio (serotypes 1-3), Haemophilus influenzae type b (Hib), pneumococcus (13 serotypes), meningococcus C, measles, mumps and rubella were measured using fluorescent bead-based multiplex immune-assays. For the correlation of antibody responses, Sp..View full abstract
Awarded by Australian National Health and Medical Research Council (NHMRC)
This work was supported by the Australian National Health and Medical Research Council (NHMRC) (grants GNT1051228 and GNT1099680). KP is supported by a Melbourne Children's Clinician-Scientist Fellowship.