Correlation of Vaccine Responses

P Zimmermann; N Ritz; KP Perrett; NL Messina; FRM van der Klis; N Curtis

Journal article

Correlation of Vaccine Responses

P Zimmermann, N Ritz, KP Perrett, NL Messina, FRM van der Klis, N Curtis

Frontiers in Immunology | FRONTIERS MEDIA SA | Published : 2021

DOI: 10.3389/fimmu.2021.646677

Open access

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Abstract

Introduction: The humoral response to vaccinations varies widely between individuals. There is no data available on the correlation between responses to different vaccines. In this study, we investigated the correlation of antibody responses between routine vaccine antigens in infants. Methods: One and seven months after the 6-month vaccinations and one month after the 12-month vaccinations, antibody concentrations to diphtheria, tetanus, pertussis, polio (serotypes 1-3), Haemophilus influenzae type b (Hib), pneumococcus (13 serotypes), meningococcus C, measles, mumps and rubella were measured using fluorescent bead-based multiplex immune-assays. For the correlation of antibody responses, Sp..

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University of Melbourne Researchers

Petra Zimmermann Author

Kirsten Perrett Author

Nicole Messina Author

Nigel Curtis Author

Grants

Awarded by Universität Basel

Funding Acknowledgements

This work was supported by the Australian National Health and Medical Research Council (NHMRC) (grants GNT1051228 and GNT1099680). KP is supported by a Melbourne Children's Clinician-Scientist Fellowship.