Journal article

Intra-patient comparison of physiologic Ga-68-PSMA-11 and F-18-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay

Medhat M Osman, Amir Iravani, Michael S Hofman, Rodney J Hicks

CANCER IMAGING | BMC | Published : 2021


BACKGROUND: Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing 68Ga -PSMA-11 and in 96.9% of patients undergoing 18F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with 18F-DCFPyL compared to 68Ga-PSMA-11. This includes more frequent visualization of cervical and sacral ganglia, which may be attributable to better imaging characteristics with 18F PET imaging. CASE PRESENTATION: This pictorial essay is to illustrate and compare, in the same patient, various representative cases of 68Ga-PSMA-11 and 18F-DCFPyL PET/CT uptake in ganglia at different anatomic locations, with different patterns ..

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