Journal article

Sequence diversity and evolution of a group of iflaviruses associated with ticks

Romain Daveu, Caroline Hervet, Louane Sigrist, Davide Sassera, Aaron Jex, Karine Labadie, Jean-Marc Aury, Olivier Plantard, Claude Rispe



We studied a group of tick-associated viruses with characteristics of members of the family Iflaviridae, a family of viruses frequently found in arthropods. Our aim was to gain insight into the evolutionary dynamics of this group of viruses, which may be linked to the biology of ticks. We explored assembled RNA-Seq data sets for different species of ticks. We identified members of five different iflavirus species, four of them novel, and discovered nine new genome sequences, including variants. Five variants represented a virus species associated with Ixodes ricinus. Unexpectedly, a sequence found in the Ixodes scapularis cell line ISE6 was nearly identical to the sequences of I. ricinus var..

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University of Melbourne Researchers


Awarded by France Genomique

Funding Acknowledgements

This work was supported by the Genoscope, the Commissariat a l'Energie Atomique et aux Energies Alternatives (CEA) and France Genomique (ANR-10-INBS-09-08), by the Italian Ministry of Education, University and Research (MIUR): Dipartimenti di Eccellenza Program (2018-2022) -Dept. of Biology and Biotechnology "L. Spallanzani", University of Pavia (to D.S.), and by a grant from the Institut Carnot France Futur Elevage (XENOBIOTICK project).