Journal article

A photoelectrochemical aptasensor for mucin 1 based on DNA/aptamer linking of quantum dots and TiO2 nanotube arrays

J Tian, T Huang, J Lu

Analytical Methods | Published : 2016


Herein, a novel strategy for the construction of a photoelectrochemical aptasensor for tumor marker mucin 1 (MUC1) was presented, which was based on the effective photoelectron transfer from CdTe quantum dots (QDs) to TiO nanotube arrays (TiO NTs) through DNA chains. First, we prepared a series of TiO NTs on titanium foil by the electrochemical anodization technique, and electrodeposited Au nanoparticles to improve their electrical conductivity and biocompatibility, which could load a high amount of MUC1 aptamers by Au-S bonds. Then, the synthesized c-DNA@QDs were immobilized on the TiO NTs by hybridization of c-DNA and aptamers to form a TiO NT/aptamer/c-DNA@QD aptasensor. Detailed stu..

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University of Melbourne Researchers


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