Journal article
Microencapsulation of growth factors by microfluidic system
LM Caballero-Aguilar, S Duchi, A Quigley, C Onofrillo, C Di Bella, SE Moulton
Methodsx | Published : 2021
Open access
Abstract
The encapsulation of growth factors is an important component of tissue engineer- ing. Using microspheres is a convenient approach in which the dose of factors can be regulated by increasing or decreasing the number of encapsulated microspheres. Moreover, microspheres offer the possibility of delivering the growth factors directly to the target site. However, the fabrication of microspheres by traditional emulsion methods is largely variable due to the experimental procedure. We have developed a protocol using a commercially available microfluidic system that allows formation of tunable particle-size droplets loaded with growth factors. The methodology includes a guide for preparing an algin..
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Awarded by Sylvia and Charles Viertel Charitable Foundation
Funding Acknowledgements
[ "Funding from the Australian Research Council Centre of Excellence Scheme (Project Number 140100012 CE) is gratefully acknowledged. Funding from St. Vincent's hospital Research Endowment Fund (Project Number 88184). The Sylvia and Charles Viertel Charitable Foundation, Clinical Investigator Award (VIERCI2118003). Studio Tulum (R) for graphical visualization.Author contributions statement", "L.M.C.A. developed and wrote the manuscript and performed the study. S.D. developed the protocol, performed the study and designed the experiment. C.O. designed the experiment and performed the study. A.Q. developed the protocol. C.B. and S.E.M. supervised the study and helped in writing the manuscript." ]