Journal article

Self-other referential neural processing in social anxiety disorder and major depressive disorder

Laura Finlayson-Short, Ben J Harrison, Christopher Davey

NEUROIMAGE-CLINICAL | ELSEVIER SCI LTD | Published : 2021

Abstract

BACKGROUND: Social anxiety disorder (SAD) and major depressive disorder (MDD) are highly comorbid and share impairments in self-referential and social processing. Many naturalistic judgements activate these processes concurrently, which can be referred to as "self-other referential processing". We sought to examine its neural correlates in young people with SAD and MDD using a novel experimental task. METHODS: Fifty six young people aged 16 to 25 with diagnoses of SAD and/or MDD (15 with SAD [M = 20.3 years, 60% female], 17 with MDD [M = 19.8 years, 53% female], 24 with comorbid SAD and MDD [M = 19.8 years, 67% female]) and 76 age and gender-matched healthy controls (HCs; M = 20.7 years, 66%..

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)


Awarded by NHMRC Career Development Fellowships


Funding Acknowledgements

The study was supported by National Health and Medical Research Council of Australia (NHMRC) Project Grants 1064643 and 1145010 (principal investigator, BJH) . CGD and BJH were supported by NHMRC Career Development Fellowships (1141738 and 1124472, respectively) .