Journal article

Association of Pulmonary Function With Cognitive Decline in Older Adults: A Nationwide Longitudinal Study in China

Xianwen Shang, David Scott, Roseanne Kimberley Chan, Lei Zhang, Mingguang He

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | OXFORD UNIV PRESS INC | Published : 2021

Abstract

This study aimed to examine whether pulmonary function and cognition are independently associated at multiple time points. We included 8264 participants (49.9% women) aged 50-94 years at baseline from the China Health and Retirement Longitudinal Study in our analysis. Participants were enrolled in 2011 and followed up in 2013 and 2015. Cognitive function was assessed through a face-to-face interview in each survey. Pulmonary function was assessed via peak expiratory flow. Pulmonary function and cognitive function decreased significantly with age in both genders. Individuals in quintile 5 of pulmonary function had a relative increase in immediate memory (β [95% CI]: 0.19 [0.09, 0.30]) and del..

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Grants

Awarded by Behavioral and Social Research division of the National Institute on Aging of the National Institute of Health


Awarded by Natural Science Foundation of China


Awarded by World Bank


Funding Acknowledgements

This work was supported by the Behavioral and Social Research division of the National Institute on Aging of the National Institute of Health (grants 1-R21-AG031372-01, 1-R01-AG037031-01, and 3-R01AG037031-03S1); the Natural Science Foundation of China (grants 70773002, 70910107022, and 71130002), the World Bank (contracts 7145915 and 7159234), and Peking University. There is no funding for the publication of this work.