Serum amyloid A levels and alpha 2 and gamma globulins on serum protein electrophoresis in cats exposed to and infected with Leishmania infantum
Giulia Savioli, Joy Archer, Emanuele Brianti, Giovanni Benelli, Manuela Schnyder, Roberta Iatta, Domenico Otranto, Cinzia Cantacessi
PARASITES & VECTORS | BMC | Published : 2021
BACKGROUND: Dogs are the main reservoir hosts of Leishmania infantum; nevertheless, recent investigations indicate a likely role for cats in the epidemiology of Leishmania infection. Feline leishmaniosis (FeL) remains poorly characterised, partly due to the lack of suitable diagnostic tools. This study aimed to compare serum amyloid A (SAA) levels and serum protein electrophoresis (SPE) profiles (specifically, alpha 2 and gamma globulins) in cats naturally exposed to or infected by L. infantum from southern Italy versus those of healthy controls and versus cats with neoplastic or inflammatory conditions from non-endemic areas. METHODS: Serum or plasma samples from four cohorts of cats were a..View full abstract
The study was a veterinary final year elective project funded internally by the University of Cambridge Department of Veterinary Medicine.