Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019-A Systematic Review and Meta-Analysis
Mallikarjuna Ponnapa Reddy, Ashwin Subramaniam, Afsana Afroz, Baki Billah, Zheng Jie Lim, Alexandr Zubarev, Gabriel Blecher, Ravindranath Tiruvoipati, Kollengode Ramanathan, Suei Nee Wong, Daniel Brodie, Eddy Fan, Kiran Shekar
CRITICAL CARE MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021
OBJECTIVES: Several studies have reported prone positioning of nonintubated patients with coronavirus diseases 2019-related hypoxemic respiratory failure. This systematic review and meta-analysis evaluated the impact of prone positioning on oxygenation and clinical outcomes. DESIGN AND SETTING: We searched PubMed, Embase, and the coronavirus diseases 2019 living systematic review from December 1, 2019, to November 9, 2020. SUBJECTS AND INTERVENTION: Studies reporting prone positioning in hypoxemic, nonintubated adult patients with coronavirus diseases 2019 were included. MEASUREMENTS AND MAIN RESULTS: Data on prone positioning location (ICU vs non-ICU), prone positioning dose (total minutes/..View full abstract
Drs. Brodie and Fan received funding from ALung Technologies. Dr. Brodie received funding from Abiomed, Xenios, Baxter, and Hemovent. Dr. Fan received funding from Getinge, Fresenius Medical Care, and MC3 Cardiopulmonary. The remaining authors have disclosed that they do not have any potential conflicts of interest.