PET/CT in Melanoma (Additional Teaching Cases)

Abstract

In this pictorial review chapter, we present a series of cases highlighting the utility of nuclear medicine in melanoma management and outline some important pitfalls. We highlight the ability of SPECT/CT to demonstrate atypical drainage pathways that are difficult to identify on conventional planar imaging. Whilst SPECT/CT enables precise localisation of sentinel nodes, there is reduced sensitivity near the site of injection owing to flare of activity which may result in false-negative findings. For PET/CT, we demonstrate the high sensitivity of PET to detect sub-centimetre metastases, and its essential application prior to surgical intervention to accurately stage the patient and also the ..