Journal article

PROVE-Pre-Eclampsia Obstetric Adverse Events: Establishment of a Biobank and Database for Pre-Eclampsia

Lina Bergman, Karl Bergman, Eduard Langenegger, Ashley Moodley, Stephanie Griffith-Richards, Johan Wikstrom, David Hall, Lloyd Joubert, Philip Herbst, Sonja Schell, Teelkien van Veen, Michael Belfort, Stephen YC Tong, Susan Walker, Roxanne Hastie, Catherine Cluver

CELLS | MDPI | Published : 2021


Pre-eclampsia is a leading cause of maternal and perinatal morbidity and mortality. The burden of disease lies mainly in low-middle income countries. The aim of this project is to establish a pre-eclampsia biobank in South Africa to facilitate research in the field of pre-eclampsia with a focus on phenotyping severe disease.The approach of our biobank is to collect biological specimens, detailed clinical data, tests, and biophysical examinations, including magnetic resonance imaging (MRI) of the brain, MRI of the heart, transcranial Doppler, echocardiography, and cognitive function tests.Women diagnosed with pre-eclampsia and normotensive controls are enrolled in the biobank at admission to ..

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Funding Acknowledgements

This study is supported by STINT; The Swedish Foundation of International Cooperation in Research and Higher Education, Pre-eclampsia Foundation, Marta Lundqvist's foundation, Ester Asberg's foundation, Jane and Dan Olsson's foundation, Center for Clinical research Dalarna, the Swedish Society of Medicine, the Swedish Research Council and the Mercy Health Foundation.