Journal article

Life after surgical resection of a low-grade glioma: A prospective cross-sectional study evaluating health-related quality of life

Ken X Teng, Benjamin Price, Shubhum Joshi, Lobna Alukaidey, Ameer Shehab, Kristy Mansour, Gurvinder S Toor, Rosemary Angliss, Katharine Drummond

JOURNAL OF CLINICAL NEUROSCIENCE | ELSEVIER SCI LTD | Published : 2021

Abstract

Health related quality of life (HRQoL) has become an important consideration in LGG patients. We report the largest prospective, longitudinal, cross-sectional cohort study of HRQoL in LGG patients, aiming to identify actionable determinants of HRQoL. Post-operative LGG adults at a large tertiary center underwent HRQoL assessment using the EORTC QLQ-C30 questionnaire administered at follow-up visits and by mail. Scores at 12 month intervals were compared with those from a normative reference population. Spearman's Rho was used to evaluate correlation of subdomain and symptom scores with global HRQoL and change over time. There were 167 participants and 366 questionnaires analysed. Patients re..

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